Giovanni Lentini Selected Research

lubeluzole

2/2021	Lubeluzole: from anti-ischemic drug to preclinical antidiarrheal studies.
1/2018	Molecular Insights into hERG Potassium Channel Blockade by Lubeluzole.
6/2016	The chemosensitizing agent lubeluzole binds calmodulin and inhibits Ca(2+)/calmodulin-dependent kinase II.
9/2013	A convenient synthesis of lubeluzole and its enantiomer: evaluation as chemosensitizing agents on human ovarian adenocarcinoma and lung carcinoma cells.

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Giovanni Lentini Research Topics

Disease

6	Neoplasms (Cancer) 01/2021 - 01/2016
4	Myotonia 12/2021 - 02/2012
3	Inflammation (Inflammations) 01/2021 - 01/2017
2	COVID-19 09/2021 - 04/2020
2	Cardiotoxicity 01/2021 - 01/2020
2	Hepatocellular Carcinoma (Hepatoma) 01/2021 - 01/2020
2	Pain (Aches) 01/2018 - 01/2015
2	Neuralgia (Stump Neuralgia) 01/2018 - 02/2012
2	Adenocarcinoma 06/2016 - 09/2013
2	Carcinoma (Carcinomatosis) 06/2016 - 09/2013
2	Cardiac Arrhythmias (Arrythmia) 10/2015 - 07/2013
2	Chronic Pain 01/2015 - 02/2013
1	Mitochondrial Diseases (Mitochondrial Disease) 05/2022
1	Cytokine Release Syndrome 09/2021
1	Infections 09/2021
1	Diarrhea 02/2021
1	Reperfusion Injury 01/2021
1	Wounds and Injuries (Trauma) 12/2020
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 07/2020
1	Hypertension (High Blood Pressure) 01/2020
1	Myotonic Disorders (Paramyotonia Congenita) 01/2018
1	Ischemic Stroke 01/2018
1	Long QT Syndrome 01/2018
1	Tinnitus 01/2018
1	Trigeminal Neuralgia (Tic Douloureux) 01/2018
1	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2017
1	Muscular Diseases (Myopathy) 01/2017
1	Multiple Myeloma 01/2017
1	Erythema Nodosum 01/2017
1	Crohn Disease (Crohn's Disease) 01/2017
1	Morning Sickness 01/2017
1	Breast Neoplasms (Breast Cancer) 01/2017
1	Rheumatoid Arthritis 01/2017
1	Sarcoidosis (Schaumann Disease) 01/2017
1	Muscular Dystrophies (Muscular Dystrophy) 01/2017
1	Epilepsy (Aura) 02/2013

Drug/Important Bio-Agent (IBA)

7	Pharmaceutical PreparationsIBA 02/2021 - 01/2016
4	Proteins (Proteins, Gene)FDA Link 05/2022 - 01/2017
4	lubeluzoleIBA 02/2021 - 09/2013
4	Mexiletine (Mexitil)FDA LinkGeneric 01/2021 - 02/2012
3	Sodium Channel BlockersIBA 12/2021 - 02/2013
3	AntioxidantsIBA 01/2021 - 01/2017
2	Tocainide (Tonocard)FDA Link 12/2021 - 01/2018
2	CytokinesIBA 09/2021 - 01/2020
2	GlycosidesIBA 01/2021 - 03/2018
2	Lysophosphatidic Acid ReceptorsIBA 01/2021 - 01/2020
2	benzothiazoleIBA 07/2020 - 01/2018
2	Thalidomide (Thalomid)FDA Link 01/2017 - 01/2017
1	Mitochondrial Proteins (Mitochondrial Protein)IBA 05/2022
1	Mitochondrial RNAIBA 05/2022
1	Dendrimers (Dendrons)IBA 09/2021
1	Antiviral Agents (Antivirals)IBA 09/2021
1	Anti-Bacterial Agents (Antibiotics)IBA 02/2021
1	AcidsIBA 01/2021
1	Cardiotonic Agents (Cardiac Stimulants)IBA 01/2021
1	EstersIBA 01/2021
1	Ether (Diethyl Ether)IBA 01/2021
1	LigandsIBA 01/2021
1	PatulinIBA 12/2020
1	DexpramipexoleIBA 07/2020
1	Riluzole FDA LinkGeneric 07/2020
1	Chloroquine (Aralen)FDA LinkGeneric 04/2020
1	Peptides (Polypeptides)IBA 01/2020
1	Whey ProteinsIBA 01/2020
1	Pregnane X ReceptorIBA 01/2020
1	genipinIBA 03/2018
1	Uncoupling Protein 2IBA 03/2018
1	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2018
1	IridoidsIBA 03/2018
1	geniposideIBA 03/2018
1	pyrrolineIBA 01/2017
1	VimentinIBA 01/2017
1	NF-kappa B (NF-kB)IBA 01/2017
1	Hypnotics and Sedatives (Sedatives)IBA 01/2017
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2017
1	Cadherins (E-Cadherin)IBA 01/2017
1	Interleukin-6 (Interleukin 6)IBA 01/2017
1	Neuroprotective AgentsIBA 06/2016
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 01/2016
1	3-hydroxymexiletineIBA 10/2015
1	Voltage-Gated Sodium ChannelsIBA 01/2015
1	Paclitaxel (Taxol)FDA LinkGeneric 09/2013
1	Doxorubicin (Adriamycin)FDA LinkGeneric 09/2013
1	Vasodilator Agents (Vasodilators)IBA 07/2013
1	Protein Isoforms (Isoforms)IBA 02/2013
1	ProdrugsIBA 02/2012

Therapy/Procedure

1	Therapeutics 10/2017
1	Drug Therapy (Chemotherapy) 02/2013